At approximately 12:53 a.m., the Earth will begin to position itself between the moon and the sun for the first of four total eclipses set to take place until September 2015.
The moon will be completely covered by the Earth's umbral shadow for the first of four eclipses, also known as a tetrad.
The full moon will change to a "reddish hue" instead of turning completely dark, due to a refraction of sunlight by the Earth's atmosphere.
The event can be rather unpredictable, as there was a 300 year gap between 1600 and 1900 where a tetrad didn't take place.
"Frequency sort of goes through 585-year cycles," said astrophysicist Fred Espenak, who works for NASA's Goddard Space Flight Center. "So you go through centuries where you don't have any, and centuries where you have a number of them."
After this one, the next tetrad won't begin until 2032.
North and South America, and most of the Pacific Basin will be able to see the show. The rest of the world however will experience "partial visibility or none at all, according to ABC News.
Places like Africa, central Asia, and Europe won't be able to watch by just looking up since it will take place during daytime.
The second half of the eclipse will be visible to Eastern Australia, according to Space.com.
The eclipse will begin at 1:58 a.m., as the moon moves into the shadow of the Earth.
At approximately 3:07 a.m., the total eclipse will be visible in the southwestern sky, with peak totality expected around 3:36 a.m.
The show will last for around 78 minutes.
Click here to access Griffith Observatory's live stream.
Slooh will also have a live stream of the lunar eclipse available as well.
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